Publications
Epigenetic scarring of exhausted T cells hinders memory differentiation upon eliminating chronic antigenic stimulation
Abdel-Hakeem, M., Manne, S., Beltra, J.C., Stelekati, E.,
Chen, C., Nzingha, K., Ali, M., Johnson, J.L., Giles, J.,
Mathew, D., Greenplate, A., Vahedi, G., and Wherry, E.J.
Nature Immunology
2021
Stripenn detects architectural stripes from chromatin conformation data using computer vision
Yoon, S. and Vahedi, G.
Preprint biorxiv
2021
Multiomics single-cell analysis of human pancreatic islets reveals novel cellular states in health and type 1 diabetes
Fasolino, M., Schwartz, G.W., Golson, M.L., Wang, Y.J., Morgan, A., Chengyang Liu, C., Schug, J., Liu, J., Wu, M., Traum, D., Kondo, A., May, C.L., Goldman, N., Wang, W., the HPAP Consortium, Feldman, M., Moore, J.H., Japp, A.S., Betts, M.R., Faryabi, R.B., Naji, A., Kaestner, K.H., Vahedi, G.
Preprint biorxiv
2021
Remodeling the chromatin landscape in T lymphocytes by a division of labor among transcription factors
Vahedi, G.
Immunological Reviews
2021
Exome-wide evaluation of rare coding variants
Park J, Lucas AM, Zhang X, Chaudhary K, Cho JH, Nadkarni G, Dobbyn A, Chittoor G, Josyula NS, Katz N, Breeyear JH, Ahmadmehrabi S, Drivas TG, Chavali VRM, Fasolino M, Sawada H, Daugherty A, Li Y, Zhang C, Bradford Y, Weaver J, Verma A, Judy RL, Kember RL, Overton JD, Reid JG, Ferreira MAR, Li AH, Baras A, LeMaire SA, Shen YH, Naji A, Kaestner KH, Vahedi G, Edwards TL, Chen J, Damrauer SM, Justice AE, Do R, Ritchie MD, Rader DJ.
Nature Medicine
2021
The Identity of Human Tissue-Emigrant CD8+ T Cells
Buggert, M., Vella,L.A., Nguyen, S., Wu, V., Sekine, T., Perez-Potti1, A., Maldini, C., Manne, S., Darko, S., Ransier, A., Kuri-Cervantes, L., Japp, A.S., Brody, I., Ivarsson, M., Hertwig, L., Antel, J.P., Johnson, M.E., Okoye, A, Picker, L., Vahedi, G., Sparrelid, E., Llewellyn-Lacey, S., Gostick, E, Björkström1, N., Bar-Or, A., Dori, Y., Naji, A., Canaday, D.H., Laufer, T.M, Wells, A., Price, D.A., Frank, I., Douek, D.C., Wherry, E.J, Itkin, M., Betts, M.R.
Cell
2020
SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 Are Expressed in the Microvasculature and Ducts of Human Pancreas but Are Not Enriched in beta Cells
Coate, K. C. ,Cha, J., Shrestha, S., Wang, W., Goncalves, L. M., Almaca, J., Kapp, M. E., Fasolino, M., Morgan, A., Dai, C., Saunders, D. C., Bottino, R., Aramandla, R., Jenkins, R., Stein, R., Kaestner, K. H., Vahedi, G., HPAP Consortium, Brissova, M., Powers, A. C.
Cell Metab
2020
Genetic Variation In Type 1 Diabetes Reconfigures The 3D Chromatin Organization Of T Cells And Alters Gene Expression
Fasolino M, Goldman N, Wang W, Cattau B, Zhou Y, Petrovic J, Link VM, Cote A, Chandra A, Silverman M, Joyce EF, Little SC; HPAP Consortium, Kaestner KH, Naji A, Raj A, Henao-Mejia J, Faryabi RB, Vahedi G.
Immunity
2020
Joint profiling of chromatin accessibility and CAR-T integration site analysis at population and single-cell levels
Wang, W. , Fasolino, M., Cattau, B., Goldman, N., Kong, W., Frederick, M. A., McCright, S. J., Kiani, K., Fraietta, J. A., Vahedi, G.
PNAS
2020