Publications

Aberrant TNF signaling in pancreatic lymph nodes of patients with Type 1 Diabetes

Abedi Maryam*, Rai Priyadarshini*, Zhou Yeqiao*, Liu Chengyang, Johnson Isabelle, Chandra Aditi, Fasolino Maria, Rostami Susan, Kaestner Klaus, Naji Ali, Faryabi# Robert, Vahedi# Golnaz. * co-first authors, # corresponding authors

bioRxiv

2024

Modeling type 1 diabetes progression using machine learning and single-cell transcriptomic measurements in human islets

Patil, A. R., Schug, J., Liu, C., Lahori, D., Descamps, H.C., the Human Pancreas Analysis Consortium, Naji, A., Kaestner, K.H., Faryabi, R.B. and Vahedi, G.

Cell Reports Medicine

2024

Intrinsically disordered domain of transcription factor TCF-1 is required for T cell developmental fidelity

Goldman N, Chandra A, Johnson I, Sullivan MA, Patil AR, Vanderbeck A, Jay A, Zhou Y, Ferrari EK, Mayne L, Aguilan J, Xue HH, Faryabi RB, Wherry EJ, Sidoli S, Maillard I and Vahedi G.

Nature Immunology

2023

Quantitative control of Ets1 dosage by a multi-enhancer hub promotes Th1 cell differentiation and protects from allergic inflammation

Chandra*, A., Yoon*, S., Michieletto*, M.F., Goldman, N., Ferrari, E., Abedi, M., Johnson, I., Fasolino, M., Pham, K., Joannas, L., Kee, B., Henao-Mejia# J., and Vahedi#, G.
*co-first authors
#co-corresponding authors

Immunity

2023

Single-cell expression profiling of islets generated by the Human Pancreas Analysis Program

Patil AR, Schug J, Naji A, Kaestner KH, Faryabi RB, Vahedi G.

Nature Metabolism

2023

Multiscale 3D genome organization underlies ILC2 ontogenesis and allergic airway inflammation

Michieletto* M.F., Tello-Cajiao* J.J., Mowel W.K., Chandra A., Yoon S., Joannas L., Clark, M.L., Jimenez M.T., Wright J.M., Lundgren, P., Williams A., Thaiss, C.A., Vahedi#, G., Henao-Mejia#, J.
*co-first authors
#co-corresponding authors

Nature Immunology

2022

TCF-1 promotes chromatin interactions across topologically associating domains in T cell progenitors

Wang*, W., Chandra*, A., Goldman*, N., Yoon*, S., Ferrari*, E., Nguyen, S.C., Joyce, E.F., and Vahedi, G.
*co-first authors

Nature Immunology

2022

Stripenn detects architectural stripes from chromatin conformation data using computer vision

Yoon, S., Chandra, A. and Vahedi, G.

Nature Communications

2022

Single-cell multi-omics analysis of human pancreatic islets reveals novel cellular states in type 1 diabetes

Fasolino M, Schwartz GW, Patil AR, Mongia A, Golson ML, Wang YJ, Morgan A, Liu C, Schug J, Liu J, Wu M, Traum D, Kondo A, May CL, Goldman N, Wang W, Feldman M, Moore JH, Japp AS, Betts MR; HPAP Consortium, Faryabi RB, Naji A, Kaestner KH, Vahedi G.

Nature Metabolism

2022