Publications
Aberrant TNF signaling in pancreatic lymph nodes of patients with Type 1 Diabetes
Abedi Maryam*, Rai Priyadarshini*, Zhou Yeqiao*, Liu Chengyang, Johnson Isabelle, Chandra Aditi, Fasolino Maria, Rostami Susan, Kaestner Klaus, Naji Ali, Faryabi# Robert, Vahedi# Golnaz. * co-first authors, # corresponding authors
bioRxiv
2024
Modeling type 1 diabetes progression using machine learning and single-cell transcriptomic measurements in human islets
Patil, A. R., Schug, J., Liu, C., Lahori, D., Descamps, H.C., the Human Pancreas Analysis Consortium, Naji, A., Kaestner, K.H., Faryabi, R.B. and Vahedi, G.
Cell Reports Medicine
2024
Intrinsically disordered domain of transcription factor TCF-1 is required for T cell developmental fidelity
Goldman N, Chandra A, Johnson I, Sullivan MA, Patil AR, Vanderbeck A, Jay A, Zhou Y, Ferrari EK, Mayne L, Aguilan J, Xue HH, Faryabi RB, Wherry EJ, Sidoli S, Maillard I and Vahedi G.
Nature Immunology
2023
Quantitative control of Ets1 dosage by a multi-enhancer hub promotes Th1 cell differentiation and protects from allergic inflammation
Chandra*, A., Yoon*, S., Michieletto*, M.F., Goldman, N., Ferrari, E., Abedi, M., Johnson, I., Fasolino, M., Pham, K., Joannas, L., Kee, B., Henao-Mejia# J., and Vahedi#, G.
*co-first authors
#co-corresponding authors
Immunity
2023
Single-cell expression profiling of islets generated by the Human Pancreas Analysis Program
Patil AR, Schug J, Naji A, Kaestner KH, Faryabi RB, Vahedi G.
Nature Metabolism
2023
Multiscale 3D genome organization underlies ILC2 ontogenesis and allergic airway inflammation
Michieletto* M.F., Tello-Cajiao* J.J., Mowel W.K., Chandra A., Yoon S., Joannas L., Clark, M.L., Jimenez M.T., Wright J.M., Lundgren, P., Williams A., Thaiss, C.A., Vahedi#, G., Henao-Mejia#, J.
*co-first authors
#co-corresponding authors
Nature Immunology
2022
TCF-1 promotes chromatin interactions across topologically associating domains in T cell progenitors
Wang*, W., Chandra*, A., Goldman*, N., Yoon*, S., Ferrari*, E., Nguyen, S.C., Joyce, E.F., and Vahedi, G.
*co-first authors
Nature Immunology
2022
Topologically associating domains are disrupted by evolutionary genome rearrangements forming species-specific enhancer connections in mice and humans
Gilbertson SE, Walter HC, Gardner K, Wren SN, Vahedi G, Weinmann AS.
Cell Reports
2022
Stripenn detects architectural stripes from chromatin conformation data using computer vision
Yoon, S., Chandra, A. and Vahedi, G.
Nature Communications
2022
Single-cell multi-omics analysis of human pancreatic islets reveals novel cellular states in type 1 diabetes
Fasolino M, Schwartz GW, Patil AR, Mongia A, Golson ML, Wang YJ, Morgan A, Liu C, Schug J, Liu J, Wu M, Traum D, Kondo A, May CL, Goldman N, Wang W, Feldman M, Moore JH, Japp AS, Betts MR; HPAP Consortium, Faryabi RB, Naji A, Kaestner KH, Vahedi G.
Nature Metabolism
2022