Publications

The epigenetic landscape of fate decisions in T cells
Jay, A., Pondevida, CM, and Vahedi, G.
Nature Immunology
2025

Aberrant TNF signaling in pancreatic lymph nodes of patients with Type 1 Diabetes
Abedi Maryam*, Rai Priyadarshini*, Zhou Yeqiao*, Liu Chengyang, Johnson Isabelle, Chandra Aditi, Fasolino Maria, Rostami Susan, Kaestner Klaus, Naji Ali, Faryabi# Robert, Vahedi# Golnaz. * co-first authors, # corresponding authors
bioRxiv
2024

Modeling type 1 diabetes progression using machine learning and single-cell transcriptomic measurements in human islets
Patil, A. R., Schug, J., Liu, C., Lahori, D., Descamps, H.C., the Human Pancreas Analysis Consortium, Naji, A., Kaestner, K.H., Faryabi, R.B. and Vahedi, G.
Cell Reports Medicine
2024

Intrinsically disordered domain of transcription factor TCF-1 is required for T cell developmental fidelity
Goldman N, Chandra A, Johnson I, Sullivan MA, Patil AR, Vanderbeck A, Jay A, Zhou Y, Ferrari EK, Mayne L, Aguilan J, Xue HH, Faryabi RB, Wherry EJ, Sidoli S, Maillard I and Vahedi G.
Nature Immunology
2023

Quantitative control of Ets1 dosage by a multi-enhancer hub promotes Th1 cell differentiation and protects from allergic inflammation
Chandra*, A., Yoon*, S., Michieletto*, M.F., Goldman, N., Ferrari, E., Abedi, M., Johnson, I., Fasolino, M., Pham, K., Joannas, L., Kee, B., Henao-Mejia# J., and Vahedi#, G.
*co-first authors
#co-corresponding authors
Immunity
2023

Single-cell expression profiling of islets generated by the Human Pancreas Analysis Program
Patil AR, Schug J, Naji A, Kaestner KH, Faryabi RB, Vahedi G.
Nature Metabolism
2023

Multiscale 3D genome organization underlies ILC2 ontogenesis and allergic airway inflammation
Michieletto* M.F., Tello-Cajiao* J.J., Mowel W.K., Chandra A., Yoon S., Joannas L., Clark, M.L., Jimenez M.T., Wright J.M., Lundgren, P., Williams A., Thaiss, C.A., Vahedi#, G., Henao-Mejia#, J.
*co-first authors
#co-corresponding authors
Nature Immunology
2022

TCF-1 promotes chromatin interactions across topologically associating domains in T cell progenitors
Wang*, W., Chandra*, A., Goldman*, N., Yoon*, S., Ferrari*, E., Nguyen, S.C., Joyce, E.F., and Vahedi, G.
*co-first authors
Nature Immunology
2022

Topologically associating domains are disrupted by evolutionary genome rearrangements forming species-specific enhancer connections in mice and humans
Gilbertson SE, Walter HC, Gardner K, Wren SN, Vahedi G, Weinmann AS.
Cell Reports
2022

Stripenn detects architectural stripes from chromatin conformation data using computer vision
Yoon, S., Chandra, A. and Vahedi, G.
Nature Communications
2022