Publications
Lineage-determining transcription factors constrain cohesin to drive multi-enhancer oncogene regulation
Zhou* Y, Jay* A, Burget N, Friedrich T, Yoon S, Alsing J, Nir G, Grosschedl R, Vahedi# G, Faryabi# RB. # co-corresponding, * co-first authors
Nature Cell Biology
2025
Joint profiling of gene expression and chromatin accessibility in pancreatic lymph nodes and spleens in human type 1 diabetes
Abedi* M, Rai* P, Zhou* Y, Liu C, Johnson I, Chandra A, Fasolino M, Rostami S, Wang W, Min Z, Li Y, Yu M, Jay A, Lian V, Silverman M, Kaestner KH, Naji A, Faryabi# RB, Vahedi# G. # co-corresponding, * co-first authors
Science Immunology
2025
Inference of multi-enhancer interactions in T lymphocytes using Hi-Cociety
Yoon, S., and Vahedi, G.
bioRxiv
2025
Single-Allele Chromatin Tracing Reveals Genomic Clustering of Paralogous Transcription Factors as a Mechanism for Developmental Robustness in T Cells
Jay, A., Zhou, Y., Yoon, S., Abeje, B., Chandra, A., Wald, J., Raj, A., Faryabi, RB, Vahedi, G.
biorXiv
2025
The epigenetic landscape of fate decisions in T cells
Jay, A., Pondevida, CM, and Vahedi, G.
Nature Immunology
2025
Modeling type 1 diabetes progression using machine learning and single-cell transcriptomic measurements in human islets
Patil, A. R., Schug, J., Liu, C., Lahori, D., Descamps, H.C., the Human Pancreas Analysis Consortium, Naji, A., Kaestner, K.H., Faryabi, R.B. and Vahedi, G.
Cell Reports Medicine
2024
Intrinsically disordered domain of transcription factor TCF-1 is required for T cell developmental fidelity
Goldman N, Chandra A, Johnson I, Sullivan MA, Patil AR, Vanderbeck A, Jay A, Zhou Y, Ferrari EK, Mayne L, Aguilan J, Xue HH, Faryabi RB, Wherry EJ, Sidoli S, Maillard I and Vahedi G.
Nature Immunology
2023
Quantitative control of Ets1 dosage by a multi-enhancer hub promotes Th1 cell differentiation and protects from allergic inflammation
Chandra*, A., Yoon*, S., Michieletto*, M.F., Goldman, N., Ferrari, E., Abedi, M., Johnson, I., Fasolino, M., Pham, K., Joannas, L., Kee, B., Henao-Mejia# J., and Vahedi#, G.
*co-first authors
#co-corresponding authors
Immunity
2023
Single-cell expression profiling of islets generated by the Human Pancreas Analysis Program
Patil AR, Schug J, Naji A, Kaestner KH, Faryabi RB, Vahedi G.
Nature Metabolism
2023
Multiscale 3D genome organization underlies ILC2 ontogenesis and allergic airway inflammation
Michieletto* M.F., Tello-Cajiao* J.J., Mowel W.K., Chandra A., Yoon S., Joannas L., Clark, M.L., Jimenez M.T., Wright J.M., Lundgren, P., Williams A., Thaiss, C.A., Vahedi#, G., Henao-Mejia#, J.
*co-first authors
#co-corresponding authors
Nature Immunology
2022